Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 2-(2-(2-bromoethoxy)ethoxy)ethyl methanesulfonate | 2702323-73-5 | 95.0% | C7H15BrO5S | 10MG
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A PEG-based bifunctional linker with a bromide and a methanesulfonate functional group, designed for use in the synthesis and assembly of PROTAC molecules. It provides a short, flexible PEG3 spacer to connect ligands while enabling nucleophilic substitution chemistry.
- Provides a short PEG3 spacer for flexibility and solubility.
- Contains terminal bromide and methanesulfonate groups that act as leaving groups for conjugation.
- Suitable for linker assembly and PROTAC synthesis via nucleophilic substitution.
- High research-grade purity for consistent performance.
- Available in small research sizes and supplied as a liquid for ease of handling.
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Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 369.45 g/mol | C19H31NO6 | 100 MG
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BCN-PEG3-OH is a BCN-functionalized PEG linker used for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and bioconjugation applications such as antibody-drug conjugate assembly. It provides a short PEG spacer with a reactive bicyclononyne moiety to enable site-selective conjugation without metal catalysts.
- Bcn functional group enables copper-free SPAAC click chemistry.
- Three-unit PEG spacer provides flexibility and solubility for conjugates.
- Suitable for antibody-drug conjugate synthesis and site-specific bioconjugation.
- Reactive alcohol terminus allows further functionalization or coupling reactions.
- Compact molecular weight and defined formula support precise stoichiometry in conjugation workflows.
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Medchemexpress LLC N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester | 2100306-76-9 | 95.0% | C30H54N6O11S | 100 MG
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N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a PEG-based PROTAC linker for the synthesis of PROTACs. It also functions as a click chemistry reagent, facilitating reactions with various alkyne-containing, DBCO, or BCN molecules.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Medchemexpress LLC Mal-PEG3-NH2 TFA | 2830214-77-0 | 99.1% | 386.32 g·mol⁻¹ | C14H21F3N2O7 | 10 MG
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Mal-PEG3-NH2 TFA is a linear heterobifunctional polyethylene glycol crosslinker supplied as the trifluoroacetic acid (TFA) salt. It contains a maleimide group at one end and a primary amine at the other, enabling selective conjugation to thiols and amines. It is provided as a non-degradable (non-cleavable) linker commonly used in PROTAC and ADC linker design and general bioconjugation.
- Maleimide and primary amine functional groups for thiol and amine conjugation.
- Non-degradable, non-cleavable linker suitable for PROTAC and ADC applications.
- High reported purity of 99.07%.
- Molecular weight 386.32 g·mol⁻¹.
- Available in multiple sizes including 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.
- Supplied as the trifluoroacetic acid (TFA) salt.
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Medchemexpress LLC Lipoamide-PEG3-mal | 1314378-19-2 | 99.6% | C25H41N3O7S2 | 10MG
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Lipoamide-PEG3-Mal is a PEG-based linker that combines a lipoamide (lipoic acid derivative) moiety with a terminal maleimide. It is supplied for research use as a building block in the synthesis of PROTACs and other bioconjugates, providing flexible spacing and a thiol-reactive handle for selective conjugation.
- Peg3 spacer provides flexibility and improved solubility.
- Lipoamide moiety offers a bio-relevant functional group for linkage.
- Maleimide group enables rapid and selective thiol conjugation.
- High reported purity suitable for synthetic applications.
- Available in small, research-friendly package sizes.
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Medchemexpress LLC Bcn-peg3-oh | 2126749-77-5 | 99.6% | 369.45 | C19H31NO6 | 10 MG
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BCN-PEG3-OH is a BCN-functionalized PEG linker used as a non-cleavable linker and click-chemistry reagent for bioconjugation and antibody-drug conjugate synthesis. It features a BCN group for copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) and a three-unit PEG spacer terminating in a hydroxyl group.
- Non-cleavable PEG linker for ADC synthesis
- BCN group enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Three-unit PEG spacer with terminal hydroxyl
- High purity suitable for research applications
- Available in small pack sizes for laboratory use
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Medchemexpress LLC N- Azido-PEG3 -N-bis | 250MG
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N- Azido-PEG3 -N-bis | 250MG
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Medchemexpress LLC Bis-PEG3-NHS ester | 1314378-16-9 | MFCD20227484 | 97.0% | 444.39 g·mol⁻¹ | C18H24N2O11 | 100 MG
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Bis-PEG3-NHS ester is a noncleavable, three-unit polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester termini for amine coupling. It is intended for antibody-agent conjugation and related bioconjugation chemistries, enabling formation of stable amide bonds to primary amines on proteins or small molecules.
- Noncleavable three-unit PEG spacer suitable for antibody-agent conjugation and bioconjugation.
- Two NHS ester reactive termini for efficient amine coupling to primary amines.
- White to off-white solid, convenient for bench handling.
- High purity (97.0%) with CAS 1314378-16-9 and formula C18H24N2O11.
- Storage: powder at -20°C (stable up to 3 years); in solvent at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Biotin-PEG3-SS-azide | 2866429-93-6 | 99.6% | 692.91 | C27H48N8O7S3 | 10 MG
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Biotin-PEG3-SS-azide is a cleavable three-unit polyethylene glycol linker bearing a biotin group and a terminal azide, designed for conjugation chemistry in research applications. It is suitable for click chemistry reactions and as a cleavable linker in the synthesis of antibody-drug conjugates.
- Cleavable disulfide linker provides intracellular release.
- Azide functionality enables CuAAC and strain-promoted cycloaddition.
- PEG3 spacer increases solubility and reduces steric hindrance.
- High purity supports reliable conjugation results.
- Soluble in DMSO at high concentration for in vitro use.
- Recommended storage at low temperature and protection from light to preserve stability.
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Medchemexpress LLC M-PEG5-acid | 81836-43-3 | MFCD20926398 | 95.0% | 280.31 g/mol | C12H24O7 | 1 G
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m-PEG5-acid is a monomethylated polyethylene glycol (PEG) linker terminated with a carboxylic acid group, used as a short spacer in the synthesis of PROTACs and other bioconjugates. It provides a PEG5 (approximately five ethylene oxide units) spacer with a reactive carboxylic acid for standard coupling chemistries.
- Short monomethylated PEG5 spacer with terminal carboxylic acid.
- Useful as a linker in PROTAC and conjugate synthesis.
- Molecular weight ~280.31 g/mol and formula C12H24O7.
- Typical purity around 95.0%.
- Light yellow to light brown liquid; density ~1.107 g/cm3.
- Store sealed, away from moisture; use cold storage for solutions.
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eMolecules 252881-74-6 | NH2-PEG3-C2-Boc | Ambeed | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 100mg | 506388578
NH2-PEG3-C2-Boc | Ambeed | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 100mg | 506388578
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Medchemexpress LLC Bromoacetamido-PEG3-azide | 940005-81-2 | ≥97.0% | C10H19BrN4O4 | 50 MG
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Bromoacetamido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent containing an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Medchemexpress LLC M-PEG3-azide | 74654-06-1 | 98.0% | C7H15N3O3 | 500 MG
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m-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Participates in CuAAc reactions with Alkyne groups
- Participates in SPAAC reactions with DBCO or BCN groups
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![Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202088.png-250.jpg)
Medchemexpress LLC Hydroxylamine, O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]- | 1306615-51-9 | MFCD28505530 | 95.0% | 234.25 g/mol | C8H18N4O4 | 10 MG
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Aminooxy-PEG3-azide is a PEG-based bifunctional linker containing an aminooxy (oxyamine) group and an azide group. It is used as a non-cleavable three-unit PEG spacer for antibody-drug conjugate (ADC) and PROTAC synthesis, and as an azide reagent for click chemistry reactions such as CuAAC and SPAAC.
- Bifunctional aminooxy and azide groups for oxime ligation and click chemistry.
- Non-cleavable three-unit PEG spacer suitable for ADC and PROTAC linker installation.
- Purity 95.0% and molecular weight 234.25 g/mol.
- Appearance colorless to light yellow liquid for easy handling.
- Storage: pure form -20°C (stable 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in small pack sizes, including 10 mg for small-scale synthesis.
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Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 g/mol | C12H28O4Si | 250 MG
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TBDMS-PEG3-OH is a tert-butyldimethylsilyl (TBDMS)-protected PEG3 alcohol used as a linker or spacer in organic synthesis, PROTAC construction, and drug-delivery conjugation. It provides a protected terminal alcohol for selective deprotection and coupling reactions.
- Provides a TBDMS-protected terminal alcohol for selective deprotection and coupling.
- Suitable as a PEG3 linker or spacer in medicinal chemistry and PROTAC synthesis.
- High purity (≥98%) and molecular weight 264.43 g/mol.
- Liquid, colorless to light yellow, convenient for solution-phase reactions.
- Recommended storage: pure form -20°C (long term) or 4°C (short term); in solvent store at -80°C.
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